BDBM50195003 4-(3-chloro-4-fluorophenylamino)-6-(pyridin-2-ylmethylamino)-1,7-naphthyridine-3-carbonitrile::CHEMBL376501

SMILES Fc1ccc(Nc2c(cnc3cnc(NCc4ccccn4)cc23)C#N)cc1Cl

InChI Key InChIKey=SPESZCBBGDUXEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195003   

TargetMitogen-activated protein kinase kinase kinase 8(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50195003(4-(3-chloro-4-fluorophenylamino)-6-(pyridin-2-ylme...)
Affinity DataIC50: 130nMAssay Description:Inhibition of Tpl2 kinase by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed