BDBM50194496 4-{3-[4-(4-fluoro-phenoxy)-cyclohexyl]-ureido}-benzoic acid::CHEMBL222160::cis-4-(3-(4-(4-fluorophenoxy)cyclohexyl)ureido)benzoic acid

SMILES OC(=O)c1ccc(NC(=O)N[C@H]2CC[C@H](CC2)Oc2ccc(F)cc2)cc1

InChI Key InChIKey=GVMGPQHXRIFVME-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194496   

TargetBifunctional epoxide hydrolase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50194496(cis-4-(3-(4-(4-fluorophenoxy)cyclohexyl)ureido)ben...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50194496(cis-4-(3-(4-(4-fluorophenoxy)cyclohexyl)ureido)ben...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50194496(cis-4-(3-(4-(4-fluorophenoxy)cyclohexyl)ureido)ben...)
Affinity DataIC50: 142nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate assessed as appearance of 6-methoxy-2-naphthaldehyde after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed