BDBM50194272 (+/-)-3-(cyclopropylmethyl)-6-ethyl-1,2,3,4,5,6-hexaahydro-cis-11-methyl-N-(2-[1,1'-biphenyl]-4-ylethyl)-1-oxo-2,6-methano-3-benzazocine-8-carboxamide::CHEMBL214104

SMILES CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(cc21)C(=O)NCCc1ccc(cc1)-c1ccccc1

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194272   

TargetKappa-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50194272((+/-)-3-(cyclopropylmethyl)-6-ethyl-1,2,3,4,5,6-he...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]U-69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50194272((+/-)-3-(cyclopropylmethyl)-6-ethyl-1,2,3,4,5,6-he...)
Affinity DataKi:  3.10nMAssay Description:Antagonist activity against human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50194272((+/-)-3-(cyclopropylmethyl)-6-ethyl-1,2,3,4,5,6-he...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed