BDBM50194090 9a-(3-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one::CHEMBL213457

SMILES CC1=C2c3ccc4[nH]ncc4c3CC2(Cc2cccc(F)c2)CCC1=O

InChI Key InChIKey=QSROZUUOXPPUOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194090   

TargetEstrogen receptor(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194090(9a-(3-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydroi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194090(9a-(3-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydroi...)
Affinity DataIC50: 440nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194090(9a-(3-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydroi...)
Affinity DataIC50: 1.60E+3nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed