BDBM50194081 9a-benzyl-7-hydroxy-4-methyl-1,2,9,9a-tetrahydro-3H-fluoren-3-one::CHEMBL214091

SMILES CC1=C2c3ccc(O)cc3CC2(Cc2ccccc2)CCC1=O

InChI Key InChIKey=ADTLCXAJDYLQPZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194081   

TargetEstrogen receptor(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194081(9a-benzyl-7-hydroxy-4-methyl-1,2,9,9a-tetrahydro-3...)
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity to wild type ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194081(9a-benzyl-7-hydroxy-4-methyl-1,2,9,9a-tetrahydro-3...)
Affinity DataIC50: 510nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194081(9a-benzyl-7-hydroxy-4-methyl-1,2,9,9a-tetrahydro-3...)
Affinity DataIC50: 1.50E+3nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194081(9a-benzyl-7-hydroxy-4-methyl-1,2,9,9a-tetrahydro-3...)
Affinity DataIC50: 14nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed