BDBM50194079 9a-benzyl-6-methyl-8,9,9a,10-tetrahydrofluoreno[1,2-d][1,2,3]triazol-7(3H)-one::CHEMBL378473

SMILES CC1=C2c3ccc4nn[nH]c4c3CC2(Cc2ccccc2)CCC1=O

InChI Key InChIKey=IZXPVMNCUBQKMG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194079   

TargetEstrogen receptor beta(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194079(9a-benzyl-6-methyl-8,9,9a,10-tetrahydrofluoreno[1,...)
Affinity DataIC50: 5.80E+3nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194079(9a-benzyl-6-methyl-8,9,9a,10-tetrahydrofluoreno[1,...)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194079(9a-benzyl-6-methyl-8,9,9a,10-tetrahydrofluoreno[1,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed