BDBM50193997 6-(furan-3-yl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((S)-1-methoxypropan-2-yl)pyrimidin-4-amine::CHEMBL220484::CHEMBL557844

SMILES COC[C@H](C)Nc1cc(nc(n1)-n1cnc2ccncc12)-c1ccoc1

InChI Key InChIKey=UTBPYMUVVZGFEJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50193997   

TargetTyrosine-protein kinase JAK3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193997(CHEMBL220484 | CHEMBL557844 | 6-(furan-3-yl)-2-(3H...)
Affinity DataIC50: 51nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193997(CHEMBL220484 | CHEMBL557844 | 6-(furan-3-yl)-2-(3H...)
Affinity DataIC50: 141nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193997(CHEMBL220484 | CHEMBL557844 | 6-(furan-3-yl)-2-(3H...)
Affinity DataIC50: 165nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193997(CHEMBL220484 | CHEMBL557844 | 6-(furan-3-yl)-2-(3H...)
Affinity DataIC50: 446nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed