BDBM50193977 1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-2-cyano-3-(2-phenylphenyl)guanidine::CHEMBL425985

SMILES CN(C)S(=O)(=O)c1c(Cl)ccc(N=C(NC#N)Nc2ccccc2-c2ccccc2)c1O

InChI Key InChIKey=IYZWLQHDOCJREA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193977   

TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193977(1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]...)
Affinity DataIC50: 752nMAssay Description:Displacement of [125I]IL8 from CXCR1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50193977(1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]...)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]IL8 from CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed