BDBM50193825 CHEMBL3953048

SMILES COc1c(Nc2ncc(Cl)c(Nc3ccccc3NS(C)(=O)=O)n2)ccc2CC(CCCc12)N1CCN(CCO)CC1

InChI Key InChIKey=RPKOZPSDQJWXMG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193825   

TargetInsulin receptor(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193825(CHEMBL3953048)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human INSR expressed in baculovirus using ATP as substrate after 15 mins by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2018
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193825(CHEMBL3953048)
Affinity DataIC50: 18nMAssay Description:Inhibition of human ALK expressed in baculovirus using recombinant GST PLC-gamma as substrate assessed as phosphorylation of the substrate after 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2018
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193825(CHEMBL3953048)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human FAK expressed in baculovirus after 30 mins using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2018
Entry Details Article
PubMed