BDBM50193820 CHEMBL3943066

SMILES COc1ccccc1Nc1nc(Nc2ccc3CC(CCCc3c2OC)N2CCN(CCO)CC2)ncc1Cl

InChI Key InChIKey=ZKHQZMGFQLTDQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193820   

TargetALK tyrosine kinase receptor(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193820(CHEMBL3943066)
Affinity DataIC50: 44nMAssay Description:Inhibition of human ALK expressed in baculovirus using recombinant GST PLC-gamma as substrate assessed as phosphorylation of the substrate after 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2018
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193820(CHEMBL3943066)
Affinity DataIC50: 42nMAssay Description:Inhibition of human FAK expressed in baculovirus after 30 mins using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2018
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Teva Branded Pharmaceutical Products R & D

Curated by ChEMBL
LigandPNGBDBM50193820(CHEMBL3943066)
Affinity DataIC50: 915nMAssay Description:Inhibition of recombinant human INSR expressed in baculovirus using ATP as substrate after 15 mins by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2018
Entry Details Article
PubMed