BDBM50193288 CHEMBL3925335

SMILES COc1cc(cc(c1)-c1ccccc1)C(=O)Nc1c(C)noc1C

InChI Key InChIKey=XKRINLNEHFBOFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193288   

TargetBromodomain-containing protein 4(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50193288(CHEMBL3925335)
Affinity DataIC50: 8.24E+3nMAssay Description:Inhibition of human His-tagged BRD4 BD1 (49 to 170 residues) using H-SGRGK(Ac)GGK(Ac)GLGK-(Ac)GGAK(Ac)RHRK(Biotin)-OH as substrate preincubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2018
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50193288(CHEMBL3925335)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human BRD4 BD2 (342 to 460 residues) at 30 uM preincubated for 30 mins followed by substrate addition measured after 30 mins by TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2018
Entry Details Article
PubMed