BDBM50193220 (3S,4S)-methyl 4-(4-iodophenyl)-1-methylpiperidine-3-carboxylate::CHEMBL215988::methyl 3,4-cis-N-methyl-4-(4-iodophenyl)piperidine-3-carboxylate

SMILES COC(=O)[C@@H]1CN(C)CC[C@@H]1c1ccc(I)cc1

InChI Key InChIKey=MXCAKGCIGZRYGJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50193220   

TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193220(methyl 3,4-cis-N-methyl-4-(4-iodophenyl)piperidine...)
Affinity DataKi:  167nMAssay Description:Displacement of [3H]cyanoimipramine from SERT in rat cerebral cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50193220(methyl 3,4-cis-N-methyl-4-(4-iodophenyl)piperidine...)
Affinity DataKi:  195nMAssay Description:Displacement of [3H]beta-CIT from DAT in rat caudate homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50193220(methyl 3,4-cis-N-methyl-4-(4-iodophenyl)piperidine...)
Affinity DataKi:  287nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50193220(methyl 3,4-cis-N-methyl-4-(4-iodophenyl)piperidine...)
Affinity DataKi:  323nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Aarhus

Curated by ChEMBL
LigandPNGBDBM50193220(methyl 3,4-cis-N-methyl-4-(4-iodophenyl)piperidine...)
Affinity DataKi:  855nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed