BDBM50193118 CHEMBL3904118

SMILES CC1=CC(=O)N(Nc2nc(nc3sc(C)c(C)c23)-c2cccs2)C1=O

InChI Key InChIKey=QMZMEJFJABYIMJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50193118   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50193118(CHEMBL3904118)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human FLT3 expressed in insect Sf21 cells preincubated for 15 mins followed by poly(Glu:Tyr) substrate addition for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50193118(CHEMBL3904118)
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human wild-type FLT3 (564 to end residues) expressed in baculovirus infected sf21 cells using Abltide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50193118(CHEMBL3904118)
Affinity DataIC50: 16nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50193118(CHEMBL3904118)
Affinity DataIC50: 21nMAssay Description:Inhibition of FLT3-D835Y mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed