BDBM50193086 CHEMBL3969723

SMILES CN1CC[C@H]([C@@H]1CO)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl

InChI Key InChIKey=QLUYMIVVAYRECT-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50193086   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of human CDK2/cyclin E expressed in baculovirus infected Sf9 insect cells using retinoblastoma (792 to 928 residues) as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 224nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK2/cyclin A expressed in baculovirus expression system using retinoblastoma (792 to 928 resid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 79nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of CDK7/cyclin H/MAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 63nMAssay Description:Inhibition of human N-terminal GST-tagged CDK4/cyclin D1 expressed in baculovirus infected Sf9 insect cells using retinoblastoma (792 to 928 residues...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 20nMAssay Description:Inhibition of human CDK9 (1 to 372 residues)/cyclin T1 (1 to 726 residues) in presence of 33P-ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 20nMAssay Description:Inhibition of full length recombinant C-terminal 6His-tagged human Cdk9/full-length human Cyclin T1 after 60 mins in presence of [33P]-gamma-ATP by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 63nMAssay Description:Inhibition of human GST-tagged CDK4/cyclin D1 expressed in baculovirus infected insect Sf9 cells after 30 mins in presence of [32P]-gamma-ATP by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human CDK2/cyclin E expressed in baculovirus expression system after 30 mins in presence of [gamma-33P]ATP by scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) after 30 mins in presence of [gamma-33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 63nMAssay Description:Inhibition of human CDK4/cyclin D1 expressed in baculovirus expression system after 30 mins in presence of [gamma-33P]ATP by scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Mizoram University

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 79nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Mizoram University

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 63nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Mizoram University

Curated by ChEMBL
LigandPNGBDBM50193086(CHEMBL3969723)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed