BDBM50193040 (2E)-1-(3',4'-dimethoxyphenyl)-3-(2-naphthyl)-2-propen-1-one::1-(3',4'-dimethoxyphenyl)-3-(2-naphthyl)-2-propen-1-one::1-(3,4-dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-en-1-one::CHEMBL217931

SMILES COc1ccc(cc1OC)C(=O)\C=C\c1ccc2ccccc2c1

InChI Key InChIKey=VOCWKGFFNOMSGD-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50193040   

TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193040(1-(3,4-dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-...)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant protein tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193040(1-(3,4-dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-...)
Affinity DataIC50: 1.26E+6nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193040(1-(3,4-dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-...)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193040(1-(3,4-dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed