BDBM50192879 CHEMBL3969394

SMILES c1ccc2c(c1)c(c[nH]2)C[C@@H]3C(=O)Nc4c(cccn4)N3

InChI Key InChIKey=DNASGFXXJPEUMJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192879   

TargetGlycogen synthase kinase-3 beta(Human)
Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50192879(CHEMBL3969394)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant full-length N-terminal GST tagged human GSK-3 beta expressed in baculovirus infected Sf9 insect cells using GSM as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 beta(Human)
Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50192879(CHEMBL3969394)
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to GSK-3 beta (unknown origin) after 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)