BDBM50192869 CIS-3,4-DIHYDROHAMACANTHIN B

SMILES c1cc2c(cc1Br)[nH]cc2[C@H]3C(=O)NCC(N3)c4c[nH]c5c4ccc(c5)Br

InChI Key InChIKey=OXVVLWOQGFZGEO-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192869   

TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192869(CIS-3,4-DIHYDROHAMACANTHIN B)
Affinity DataIC50: 16nMAssay Description:Inhibition of methicillin-resistant Staphylococcus aureus pyruvate kinase by coupled lactate dehydrogenase continuous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPyruvate kinase(Staphylococcus aureus (strain MRSA252))
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192869(CIS-3,4-DIHYDROHAMACANTHIN B)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)