BDBM50192834 CHEMBL3914092::US10188627, Compound 8n

SMILES CN(Cc1cc(C)ccc1OC\C=C(/C)CCC(O)=O)C(=O)c1ccc(cc1)-c1ccco1

InChI Key InChIKey=VHKFJHYXTAKRPY-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50192834   

TargetPeroxisome proliferator-activated receptor delta(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50192834(CHEMBL3914092 | US10188627, Compound 8n)
Affinity DataEC50:  23nMAssay Description:Transactivation of ProLink tagged human PPARdelta transfected in CHO-K1 cells assessed as interaction with EA labelled SRCP after 3 to 16 hrs by beta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50192834(CHEMBL3914092 | US10188627, Compound 8n)
Affinity DataEC50:  20nMAssay Description:Transactivation of human Gal4-PPARdelta LBD transfected in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50192834(CHEMBL3914092 | US10188627, Compound 8n)
Affinity DataEC50:  22.6nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetPeroxisome proliferator-activated receptor delta(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50192834(CHEMBL3914092 | US10188627, Compound 8n)
Affinity DataEC50:  19.8nMAssay Description:Cell Handling: PathHunter NHR cell lines were expanded from freezer stocks according to standard procedures. Cells were seeded in a total volume of 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetPPAR delta protein(Rat)
Mitobridge

US Patent
LigandPNGBDBM50192834(CHEMBL3914092 | US10188627, Compound 8n)
Affinity DataEC50:  22.6nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent