BDBM50192652 CHEMBL3901189

SMILES C[C@H](NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O

InChI Key InChIKey=WOVYKVDSWWPJMK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192652   

TargetC-X-C chemokine receptor type 4(Human)
Second University of Naples

Curated by ChEMBL
LigandPNGBDBM50192652(CHEMBL3901189)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of 12G5 anti-CXCR4 antibody binding to CXCR4 in human HT29 cells preincubated for 30 mins followed by antibody addition by FACS Canto II c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2018
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Second University of Naples

Curated by ChEMBL
LigandPNGBDBM50192652(CHEMBL3901189)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2018
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Second University of Naples

Curated by ChEMBL
LigandPNGBDBM50192652(CHEMBL3901189)
Affinity DataIC50: 53nMAssay Description:Displacement of [125I]-CXCL12 from CXCR4 in human CCRF-CEM cells after 1 hr by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2019
Entry Details Article
PubMed