BDBM50192548 (R)-1-(1-((2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)carbamoyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carboxylic acid::CHEMBL405543

SMILES OC(=O)c1ccc2n(C3CCN(CC3)C(=O)N[C@@H]3N=C(c4ccccc4)c4ccccc4N(CC(F)(F)F)C3=O)c(=O)[nH]c2c1

InChI Key InChIKey=QJDCOSVSBQCDSL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192548   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192548((R)-1-(1-((2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)...)
Affinity DataIC50: 715nMAssay Description:Activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192548((R)-1-(1-((2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)...)
Affinity DataKi:  810nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed