BDBM50192504 1-(3-chloro-4-fluoro-phenoxy)-7,8-dimethoxy-11-methyl-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cycloheptene::CHEMBL425620

SMILES COc1cc2CN(C)c3c(Oc4ccc(F)c(Cl)c4)ncnc3Oc2cc1OC

InChI Key InChIKey=XGBKFOGRMBLNRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192504   

TargetVascular endothelial growth factor receptor 2(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50192504(1-(3-chloro-4-fluoro-phenoxy)-7,8-dimethoxy-11-met...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDR measured as pGAT-biotin peptide phosphorylation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50192504(1-(3-chloro-4-fluoro-phenoxy)-7,8-dimethoxy-11-met...)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed