BDBM50192483 1-(3-bromo-phenylsulfanyl)-7,8-dimethoxy-10,11-dihydro-5-thia-2,4,11-triaza-dibenzo[a,d]cycloheptene::CHEMBL386456

SMILES COc1cc2CNc3c(Sc4cccc(Br)c4)ncnc3Sc2cc1OC

InChI Key InChIKey=BAQNBDHDQVLTGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192483   

TargetEpidermal growth factor receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50192483(1-(3-bromo-phenylsulfanyl)-7,8-dimethoxy-10,11-dih...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed