BDBM50192480 (7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-1-yl)-(1H-indazol-6-yl)-amine::CHEMBL215488

SMILES COc1cc2CNc3c(Nc4ccc5c[nH]nc5c4)ncnc3Oc2cc1OC

InChI Key InChIKey=GGPWEMMVSWVERZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192480   

TargetVascular endothelial growth factor receptor 2(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50192480((7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-triaza-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDR measured as pGAT-biotin peptide phosphorylation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50192480((7,8-dimethoxy-10,11-dihydro-5-oxa-2,4,11-triaza-d...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of EGFR measured as pGAT-biotin peptide phosphorylation in presence of 2.0 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed