BDBM50192424 4-(2,6-dichloro-4-hydroxyphenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL379392

SMILES Oc1ccc2[nH]c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1c(Cl)cc(O)cc1Cl

InChI Key InChIKey=HYDMUVIJBLUFLR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192424   

TargetSerine/threonine-protein kinase Chk1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50192424(4-(2,6-dichloro-4-hydroxyphenyl)-9-hydroxypyrrolo[...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition at human Chk1 in presence of 4 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50192424(4-(2,6-dichloro-4-hydroxyphenyl)-9-hydroxypyrrolo[...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human Wee1 in presence of 9.5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50192424(4-(2,6-dichloro-4-hydroxyphenyl)-9-hydroxypyrrolo[...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed