BDBM50192274 (2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-{5'-ethylspiro[indene-1,4'-piperidine]-1'-yl}-2-(4-fluorophenyl)butanamide::CHEMBL213648

SMILES CCC1CN(CC[C@H](C(=O)NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2ccc(F)cc2)CCC11C=Cc2ccccc12

InChI Key InChIKey=MIEZOKPKWGNDIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192274   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50192274((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-...)
Affinity DataIC50: 440nMAssay Description:Inhibition of [125I]MCP1 binding to CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed