BDBM50192227 3-biphenyl-4-yl-4-cyano-5-methylsulfanyl-thiophene-2-carboxylic acid::CHEMBL377662

SMILES CSc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=RZEKJVHTNOHVAI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192227   

TargetGlutamate receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192227(3-biphenyl-4-yl-4-cyano-5-methylsulfanyl-thiophene...)
Affinity DataEC50:  795nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assessed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192227(3-biphenyl-4-yl-4-cyano-5-methylsulfanyl-thiophene...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assessed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed