BDBM50191950 4-cyano-5-ethyl-3-(3'-methoxy-biphenyl-4-yl)-1-methyl-1H-pyrrole-2-carboxylic acid::CHEMBL215255

SMILES CCc1c(C#N)c(c(C(O)=O)n1C)-c1ccc(cc1)-c1cccc(OC)c1

InChI Key InChIKey=RTLYHQVKSKQSSZ-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50191950   

TargetGlutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191950(4-cyano-5-ethyl-3-(3'-methoxy-biphenyl-4-yl)-1-met...)
Affinity DataEC50:  924nMAssay Description:Activity at human recombinant iGluR2 flop expressed in HEK293 cells measured as change in intracellular calcium ion concentration in presence of glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191950(4-cyano-5-ethyl-3-(3'-methoxy-biphenyl-4-yl)-1-met...)
Affinity DataEC50:  391nMAssay Description:Activity at human recombinant iGluR2 flip expressed in HEK293 cells measured as change in intracellular calcium ion concentration in presence of glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191950(4-cyano-5-ethyl-3-(3'-methoxy-biphenyl-4-yl)-1-met...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity at human recombinant iGluR4 flop expressed in HEK293 cells measured as change in intracellular calcium ion concentration in presence of glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191950(4-cyano-5-ethyl-3-(3'-methoxy-biphenyl-4-yl)-1-met...)
Affinity DataEC50:  1.05E+3nMAssay Description:Activity at human recombinant iGluR4 flip expressed in HEK293 cells measured as change in intracellular calcium ion concentration in presence of glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed