BDBM50191826 CHEMBL378449::N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-{spiro[indene-1,4'-piperidine]-1'-yl}butanamide

SMILES FC(F)(F)c1cc(CNC(=O)CCCN2CCC3(CC2)C=Cc2ccccc32)cc(c1)C(F)(F)F

InChI Key InChIKey=VQLQJJXLQREOJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191826   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191826(N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-{spir...)
Affinity DataIC50: 570nMAssay Description:Displacement of [125I]MCP-1 from human CCR2b expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191826(N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-{spir...)
Affinity DataIC50: 570nMAssay Description:Antagonist activity at human CCR2b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed