BDBM50191815 CHEMBL214825::N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-3-hydroxy-2-{2-[(1R,5'R)-5'-methylspiro[indene-1,4'-piperidine]-1'-yl]ethyl}butanamide

SMILES CC(O)C(CCN1CC[C@@]2(C=Cc3ccccc23)[C@@H](C)C1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=LRBSYXWKXPQNJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191815   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50191815(N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-3-hydro...)
Affinity DataIC50: 48nMAssay Description:Displacement of [125I]MCP-1 from human CCR2b expressed in human monocyte cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed