BDBM50191356 CHEMBL3967915

SMILES CN1CCN(C(C1)c1ccc(Cl)cc1)C(=O)c1ccc2[nH]nc(C)c2c1

InChI Key InChIKey=QLSTWYIPABBKKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50191356   

TargetCyclin-dependent kinase 8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50191356(CHEMBL3967915)
Affinity DataIC50: 230nMAssay Description:Inhibition of CDK8 in human 7dF3 cells preincubated for 2 hrs followed by beta-oestradiol addition measured after 24 hrs by luciferase reporter gene ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2018
Entry Details Article
PubMed
TargetCyclin-C(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50191356(CHEMBL3967915)
Affinity DataIC50: 15nMAssay Description:Inhibition of Alexa647 tracer binding to full length recombinant human His-tagged CDK8/cyclin C expressed in Baculovirus expression system preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2018
Entry Details Article
PubMed