BDBM50190839 CHEMBL214435::trans-(S)-5-((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentylamino)methyl)pyrrolidin-2-one

SMILES FC(F)(F)c1cc(CO[C@@H]2CC[C@H](NC[C@@H]3CCC(=O)N3)[C@H]2c2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=XFSJGZVARSALDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190839   

TargetSubstance-P receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50190839(trans-(S)-5-((3-(3,5-bis(trifluoromethyl)benzyloxy...)
Affinity DataIC50: 260nMAssay Description:Displacement of [125I]SP from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed