BDBM50190617 CHEMBL3827626

SMILES Cc1cc(C)c(C)c(c1C)S(=O)(=O)Nc1ccc(N2CC[C@H](C2)C(O)=O)c2ccccc12

InChI Key InChIKey=BVYWIQHJXAEJOD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190617   

TargetKelch-like ECH-associated protein 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50190617(CHEMBL3827626)
Affinity DataIC50: 100nMAssay Description:Inhibition of human Keap1 kelch domain (Ala321 to Thr609 residues) binding to fluorescent labeled Nrf2 peptide preincubated for 15 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50190617(CHEMBL3827626)
Affinity DataIC50: 140nMAssay Description:Inhibition of FITC-9mer Nrf2 peptide binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed