BDBM50190604 CHEMBL209651::cis-(3R,6R)-(6-benzhydryl-tetrahydropyran-3-yl)-(4-nitrobenzyl)amine

SMILES [O-][N+](=O)c1ccc(CN[C@@H]2CC[C@@H](OC2)C(c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=UEFZKRWCBHMIDQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50190604   

TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190604(cis-(3R,6R)-(6-benzhydryl-tetrahydropyran-3-yl)-(4...)
Affinity DataKi:  60nMAssay Description:Inhibition of DAT-mediated [3H]DA uptake in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190604(cis-(3R,6R)-(6-benzhydryl-tetrahydropyran-3-yl)-(4...)
Affinity DataKi:  65nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat striatum DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190604(cis-(3R,6R)-(6-benzhydryl-tetrahydropyran-3-yl)-(4...)
Affinity DataKi:  65nMAssay Description:Inhibition of SERT-mediated [3H]5-HT uptake in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190604(cis-(3R,6R)-(6-benzhydryl-tetrahydropyran-3-yl)-(4...)
Affinity DataKi:  82nMAssay Description:Inhibition of NET-mediated [3H]NE uptake in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed