BDBM50190600 CHEMBL378437::cis-(3R,6R)-(6-benzhydryl-tetrahydropyran-3-yl)-(1H-indol-5-ylmethyl)amine

SMILES C(N[C@@H]1CC[C@@H](OC1)C(c1ccccc1)c1ccccc1)c1ccc2[nH]ccc2c1

InChI Key InChIKey=UJBRKEMHKNOCKI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50190600   

TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190600(cis-(3R,6R)-(6-benzhydryl-tetrahydropyran-3-yl)-(1...)
Affinity DataKi:  12nMAssay Description:Inhibition of SERT-mediated [3H]5-HT uptake in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190600(cis-(3R,6R)-(6-benzhydryl-tetrahydropyran-3-yl)-(1...)
Affinity DataKi:  16nMAssay Description:Inhibition of NET-mediated [3H]NE uptake in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190600(cis-(3R,6R)-(6-benzhydryl-tetrahydropyran-3-yl)-(1...)
Affinity DataKi:  142nMAssay Description:Inhibition of DAT-mediated [3H]DA uptake in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50190600(cis-(3R,6R)-(6-benzhydryl-tetrahydropyran-3-yl)-(1...)
Affinity DataKi:  467nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat striatum DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed