BDBM50190459 CHEMBL377986::N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-(4-methoxyphenyl)butyl]-guanidine

SMILES COc1ccc(CCCCN=C(N)NC(=O)c2nc(Cl)c(N)nc2N)cc1

InChI Key InChIKey=UVGRAPSNRCDSEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190459   

TargetAmiloride-sensitive sodium channel subunit alpha(Human)
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190459(N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-[4-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed