BDBM50190391 CHEMBL3826995

SMILES CN(C)c1ccc(\C=C2/N(C)C(=S)N(C2=O)c2ccc3CCCc3c2)cc1

InChI Key InChIKey=IGOQOEGCEZNIHE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190391   

TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190391(CHEMBL3826995)
Affinity DataKi:  8.04E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190391(CHEMBL3826995)
Affinity DataKi:  1.31E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed