BDBM50190390 CHEMBL3828444

SMILES Oc1cc(nn1-c1ccccn1)-c1ccccc1

InChI Key InChIKey=GHSRLQHTSTVQNM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190390   

TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190390(CHEMBL3828444)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190390(CHEMBL3828444)
Affinity DataKi:  3.12E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed