BDBM50190337 5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxybenzoic acid::CHEMBL377353

SMILES NS(=O)(=O)c1ccc(cc1)N=Nc1ccc(O)c(c1)C(O)=O

InChI Key InChIKey=NBSRUZQXRUNPNY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50190337   

TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50: 8.89E+3nMAssay Description:Inhibition of COX2 assessed as LPS-stimulated PGE2 production in human whole blood leukocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50: 2.93E+4nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of ovine COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed