BDBM50190327 CHEMBL3828285

SMILES CN1C(=S)N(C(=O)\C1=C\c1ccc(O)cc1O)c1cccc(Cl)c1

InChI Key InChIKey=OPIOXTZPSHBWQK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190327   

TargetNADPH oxidase 4(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190327(CHEMBL3828285)
Affinity DataKi:  3.38E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
TargetNADPH oxidase 1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190327(CHEMBL3828285)
Affinity DataKi:  3.45E+4nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed