BDBM50190254 6-(methylthio)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide::CHEMBL215917

SMILES CSc1cc2NCNS(=O)(=O)c2cc1S(N)(=O)=O

InChI Key InChIKey=LBJQTEKVLPSHMB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50190254   

TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190254(6-(methylthio)-3,4-dihydro-2H-1,2,4-benzothiadiazi...)
Affinity DataKi:  108nMAssay Description:Inhibition of human cloned CA12 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190254(6-(methylthio)-3,4-dihydro-2H-1,2,4-benzothiadiazi...)
Affinity DataKi:  139nMAssay Description:Inhibition of human cloned CA9 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190254(6-(methylthio)-3,4-dihydro-2H-1,2,4-benzothiadiazi...)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of human cloned CA2 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190254(6-(methylthio)-3,4-dihydro-2H-1,2,4-benzothiadiazi...)
Affinity DataKi:  1.09E+4nMAssay Description:Inhibition of human cloned CA1 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed