BDBM50190252 5-(aminosulfonyl)-N-benzyl-2-chloro-4-mercaptobenzamide::CHEMBL215291

SMILES NS(=O)(=O)c1cc(C(=O)NCc2ccccc2)c(Cl)cc1S

InChI Key InChIKey=MYHKNDAXFYJZDT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50190252   

TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190252(5-(aminosulfonyl)-N-benzyl-2-chloro-4-mercaptobenz...)
Affinity DataKi:  19.9nMAssay Description:Inhibition of human cloned CA2 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190252(5-(aminosulfonyl)-N-benzyl-2-chloro-4-mercaptobenz...)
Affinity DataKi:  35.6nMAssay Description:Inhibition of human cloned CA12 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190252(5-(aminosulfonyl)-N-benzyl-2-chloro-4-mercaptobenz...)
Affinity DataKi:  40.9nMAssay Description:Inhibition of human cloned CA9 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190252(5-(aminosulfonyl)-N-benzyl-2-chloro-4-mercaptobenz...)
Affinity DataKi:  1.97E+4nMAssay Description:Inhibition of human cloned CA1 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed