BDBM50190248 4-chloro-2-mercapto-5-(pyrrolidine-1-carbonyl)benzenesulfonamide::CHEMBL386517

SMILES NS(=O)(=O)c1cc(C(=O)N2CCCC2)c(Cl)cc1S

InChI Key InChIKey=ZUEWEISLZAHQML-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50190248   

TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190248(4-chloro-2-mercapto-5-(pyrrolidine-1-carbonyl)benz...)
Affinity DataKi:  14.5nMAssay Description:Inhibition of human cloned CA9 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190248(4-chloro-2-mercapto-5-(pyrrolidine-1-carbonyl)benz...)
Affinity DataKi:  19.6nMAssay Description:Inhibition of human cloned CA2 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190248(4-chloro-2-mercapto-5-(pyrrolidine-1-carbonyl)benz...)
Affinity DataKi:  20nMAssay Description:Inhibition of human cloned CA12 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190248(4-chloro-2-mercapto-5-(pyrrolidine-1-carbonyl)benz...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of human cloned CA1 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed