BDBM50190241 6-mercapto-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide::CHEMBL215916

SMILES NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1S

InChI Key InChIKey=GODDFNDSOAANHO-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50190241   

TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190241(6-mercapto-3,4-dihydro-2H-1,2,4-benzothiadiazine-7...)
Affinity DataKi:  8.60nMAssay Description:Inhibition of human cloned CA2 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190241(6-mercapto-3,4-dihydro-2H-1,2,4-benzothiadiazine-7...)
Affinity DataKi:  8.70nMAssay Description:Inhibition of human cloned CA2 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190241(6-mercapto-3,4-dihydro-2H-1,2,4-benzothiadiazine-7...)
Affinity DataKi:  113nMAssay Description:Inhibition of human cloned CA9 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190241(6-mercapto-3,4-dihydro-2H-1,2,4-benzothiadiazine-7...)
Affinity DataKi:  115nMAssay Description:Inhibition of human cloned CA9 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190241(6-mercapto-3,4-dihydro-2H-1,2,4-benzothiadiazine-7...)
Affinity DataKi:  117nMAssay Description:Inhibition of human cloned CA12 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190241(6-mercapto-3,4-dihydro-2H-1,2,4-benzothiadiazine-7...)
Affinity DataKi:  118nMAssay Description:Inhibition of human cloned CA12 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190241(6-mercapto-3,4-dihydro-2H-1,2,4-benzothiadiazine-7...)
Affinity DataKi:  7.30E+3nMAssay Description:Inhibition of human cloned CA1 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50190241(6-mercapto-3,4-dihydro-2H-1,2,4-benzothiadiazine-7...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of human cloned CA1 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed