BDBM50190104 CHEMBL3828053::US10618914, Compound 30::US11111253, Compound UPCDC10371

SMILES COc1ccc(cc1)C1=Nn2c(SC1CCN)nnc2-c1cc(n[nH]1)-c1ccccc1

InChI Key InChIKey=QVOHKXJSSDTGGL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50190104   

TargetSignal transducer and activator of transcription 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50190104(CHEMBL3828053 | US10618914, Compound 30 | US111112...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of IL6-induced STAT3 in human CAL33 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50190104(CHEMBL3828053 | US10618914, Compound 30 | US111112...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, HRMS),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
Go to US Patent

TargetSignal transducer and activator of transcription 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50190104(CHEMBL3828053 | US10618914, Compound 30 | US111112...)
Affinity DataIC50: 1.17E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, FIRMS)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
Go to US Patent