BDBM50190049 2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-benzamide::CHEMBL212912

SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2ccccc2Cl)c2ccccc12

InChI Key InChIKey=DDNAXKKEJCCHMD-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50190049   

Target5-hydroxytryptamine receptor 2A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190049(2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-...)
Affinity DataKi:  1nMAssay Description:Binding affinity at 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190049(2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]SCH 23390 from human dopamine D1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190049(2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190049(2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-...)
Affinity DataKi:  73nMAssay Description:Binding affinity at dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190049(2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-...)
Affinity DataKi:  181nMAssay Description:Displacement of [3H]methylspiperone from dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190049(2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-...)
Affinity DataKi:  181nMAssay Description:Displacement of [3H]methylspiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190049(2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-...)
Affinity DataKi:  181nMAssay Description:Binding affinity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190049(2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-...)
Affinity DataKi:  455nMAssay Description:Binding affinity at adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50190049(2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-...)
Affinity DataKi:  870nMAssay Description:Binding affinity at dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed