BDBM50190011 (4R,5R)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-yl)methyl)-1-methyl-4-phenylpyrrolidin-2-one::CHEMBL212754

SMILES CN1[C@@H]([C@H](O)c2ccc(s2)-c2cccnc2)[C@H](CC1=O)c1ccccc1

InChI Key InChIKey=GGJVIKJRBHCNKM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50190011   

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190011((4R,5R)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190011((4R,5R)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190011((4R,5R)-5-((S)-hydroxy(5-(pyridin-3-yl)thiophen-2-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed