BDBM50190008 (4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-2-yl)methyl)-1-methyl-4-phenylpyrrolidin-2-one::CHEMBL384404

SMILES CN1[C@@H]([C@H](O)c2ccc(s2)S(=O)(=O)c2ccccc2)[C@H](CC1=O)c1ccccc1

InChI Key InChIKey=HSIRMAVTZOFUEE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50190008   

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190008((4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190008((4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50190008((4R,5R)-5-((S)-hydroxy(5-(phenylsulfonyl)thiophen-...)
Affinity DataIC50: 480nMAssay Description:Inhibition of estradiol to estrone conversion in MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed