BDBM50189908 CHEMBL3827993

SMILES Nc1ccc(cc1NC(=O)C1Cc2ccccc2CO1)-c1ccc(F)cc1

InChI Key InChIKey=FVTBTHDXSZOXNU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189908   

TargetHistone deacetylase 1(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50189908(CHEMBL3827993)
Affinity DataIC50: 45nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged full length human recombinant HDAC1 expressed in baculovirus coexpressed in fall armyw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50189908(CHEMBL3827993)
Affinity DataIC50: 119nMAssay Description:Inhibition full length human recombinant HDAC2 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxyfluorescein (FAM)-labeled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Broad Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50189908(CHEMBL3827993)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition full length human recombinant HDAC3 expressed in baculovirus using carboxyfluorescein (FAM)-labeled acetylated/ trifluoroacetylated peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed