BDBM50189855 2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(piperidin-1-yl)imidazo[1,2-b]pyridazine::CHEMBL207543

SMILES Clc1ccc(cc1Cl)N1CCN(Cc2cn3nc(ccc3n2)N2CCCCC2)CC1

InChI Key InChIKey=ACHQQXOLWIKHRK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50189855   

TargetD(4) dopamine receptor(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50189855(2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50189855(2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(...)
Affinity DataKi:  710nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(short) in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50189855(2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(...)
Affinity DataKi:  850nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D3 in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50189855(2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(long) in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50189855(2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(...)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [3H]SCH 23990 from dopamine receptor D1 in porcine striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed