BDBM50189780 CHEMBL3827954

SMILES Cc1cccc(c1)OCC(=O)N2CCN(CC2)C(=O)c3cccc(c3OC)OC

InChI Key InChIKey=LUMCNRKHZRYQOV-UHFFFAOYSA-N

Data  1 KI  1 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50189780   

TargetChromobox protein homolog 7(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50189780(CHEMBL3827954)
Affinity DataKd:  1.25E+5nMAssay Description:Binding affinity to CBX7ChD (7 to 66 residues) (unknown origin) expressed in RIPL-BL21 (DE3)-CodonPlus competent cells assessed as compound/protein/F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetChromobox protein homolog 7(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50189780(CHEMBL3827954)
Affinity DataKd:  2.90E+4nMAssay Description:Binding affinity to Cbx7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetChromobox protein homolog 7(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50189780(CHEMBL3827954)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of Cbx7 (unknown origin) using FITC-labeled SETDB1-K1170me3 peptide as probe by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetChromobox protein homolog 7(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50189780(CHEMBL3827954)
Affinity DataKi:  3.31E+4nMAssay Description:Binding affinity to CBX7ChD (7 to 66 residues) (unknown origin) expressed in RIPL-BL21 (DE3)-CodonPlus competent cells in presence of FITC-labeled SE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)